All of the patients provided written informed consent.
HIV-infected patients regularly attending the outpatient infectious disease clinic of Cliniques universitaires Saint-Luc were recruited on a voluntary basis and without financial compensation for this study. Consecutive patients fulfilling the inclusion criteria were selected by the physician after approval of the patients to enroll in the study until 50 patients were included in the second part of the study.
The following inclusion criteria were used: The patients that were unstable defined by any modification of health outcomes for the duration of the study were excluded from the second phase of the study. The study included two phases. They were asked to fill out these questionnaires while attending the consultation Phase I. During this time, they received a second package including the questionnaires with a stamped and addressed reply envelope. They were asked to fill out these questionnaires 15 days later and then send them back so that the responses obtained during the initial visit could be compared with the later responses Phase II.
Trained researchers were present to provide assistance in completing the questionnaires if necessary. Both French translations were performed, and any resulting issues were resolved. One independent translator translated this new version back into English, and the translation was compared to the original version. This translator was a native English speaker. In the original version, socio-demographic information regarding sex and age are obtained.
General health status is evaluated by asking the subjects to rate his or her health on the Likert scale, which ranges from very poor 1 to very good 5.
All of the items are rated on a five-point scale not at all to extremely for the intensity and capacity domains; never to always for frequency; very dissatisfied to very satisfied or very good to very poor for evaluation. For negatively framed items, the scores are reversed so that the higher the score, the better the QoL. A score is calculated from the facet and domain. Each item of a facet and facet of a domain contribute equally to the facet and domain scores, respectively.
The SF is an auto-evaluation short-form health instrument  ,  and was previously validated in French . This form includes 36 items and covers eight different scales: A linear transformation on a 0 to scale the lower the score, the worse the status was performed. The physical component summary PCS and mental component summary MCS were also calculated by aggregating the 8 previous scales.
The data were computed using SPSS A descriptive analysis was performed for the socio-demographic and HIV-related information. The validity was measured using Pearson correlations to determine the strength of the relationship between the scores for the hypothesised interrelated domains from the two instruments and between each item and its domain for the WHOQOL-HIV. The hypothesised interrelation was based on two expert opinions.
Their final decisions were based on their own opinion and consensual. The test-retest reliability was evaluated using an intra-class coefficient ICC for agreement, and agreement was estimated using the Bland Altman method. The correlations between the variables were measured using ICCs  — .
The ICCs determine the extent of the relative discrepancies between the evaluations and give the proportion of variance attributable to differences between the groups. The effect size was calculated for each domain and item by taking the difference between the mean baseline and follow-up scores on the measurement and dividing by the standard deviation of the baseline scores. All of the tests were two-tailed with a statistical significance level fixed at a p value of 0.
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Among the 64 enrolled subjects in the first phase, 50 were included in phase II of the study. The patients who were not included either did not complete or did not return the questionnaires or were hospitalised during this period. The socio-demographic data of the patients are summarised in Table 1. Sixteen percent of the patients were classified as CDC stage C.
The facet-domain correlations ranging between 0. The results of the validation process revealed statistically significant correlations between the overall quality of life and different domains of WHOQOL-HIV, with all of the coefficients ranging from 0. The Centre d'assistance et d'accompagnement aux plaintes CAAP is a regional community organization mandated by the Minister of Health and Social Services to provide free and confidential services to assist and support you in filing a complaint.
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